Faculty

Kathlyn A. ParkerKathlyn A. Parker, Professor

B.A Northwestern University, 1966
Ph.D. Stanford University, 1970
Postdoctoral Fellow, Columbia University, 1971-1973

 

Phone: (631) 632-7851

Email:

 

 

 

Organic Chemistry

Synthesis of natural products; methods of synthesis; especially those involving regio- and stereochemical problems; synthesis and study of modified biological molecules.

Research in Professor Parker's group is focussed on the synthesis of compounds of biological interest. Goals include the development of synthetic methods, the invention of new strategies with total synthesis as the eventual goal, and the design and preparation of modified structures with predicted biological properties.

Awards/Honors

  • Dreyfus Teacher-Scholar
  • Sloan Fellow
  • NSF Visiting Professorship for Women, Columbia University, 1987-1988
  • Guggenheim Fellow, 1988
  • NSF Career Advancement Award, 1993

Publications

Parker, Kathlyn A.; Wang, Peng. Deconstruction-Reconstruction Strategy for Accessing Valuable Polyketides. Preparation of the C15-C24 Stereopentad of Discodermolide. Organic Letters     ACS ASAP. DOI: 10.1021/ol702144u

Parker, Kathlyn A.; Cao, Huanyan. Scalable, Catalytic Asymmetric Synthesis of Syn, Anti Stereotriad Building Blocks for Polypropionate Antibiotics. Organic Letters  (2006),  8(16),  3541-3544.  http://pubs.acs.org/cgi-bin/abstract.cgi/orlef7/2006/8/i16/abs/ol0612612.html

Parker, Kathlyn A.; Wang, Zhongyu. Cleavable Chiral Auxiliaries in 8p  (8p , 6p ) Electrocyclizations.  Organic Letters  (2006),  8(16),  3553-3556.  http://pubs.acs.org/cgi-bin/abstract.cgi/orlef7/2006/8/i16/abs/ol061328l.html

Parker, Kathlyn A.; Mindt, Thomas L.; Koh, Yung-hyo. TESOTf-Induced Rearrangement of Quinols. Efficient Construction of the Fully Functionalized Carbon Skeleton of the Griseusins by a Divergent-Reconvergent Approach.  Organic Letters  (2006),  8(9),  1759-1762.  http://pubs.acs.org/cgi-bin/abstract.cgi/orlef7/2006/8/i09/abs/ol060206q.html

Lee, Jae Chul; Parker, Kathlyn A.; Sampson, Nicole S. Amino Acid-Bearing ROMP Polymers with a Stereoregular Backbone.  Journal of the American Chemical Society (2006),  128(14),  4578-4579.  http://pubs.acs.org/cgi-bin/abstract.cgi/jacsat/2006/128/i14/abs/ja058801v.html

Parker, Kathlyn A.; Fokas, Demosthenes. Enantioselective Synthesis of (-)-Dihydrocodeinone: A Short Formal Synthesis of (-)-Morphine. Journal of Organic Chemistry (2006), 71(2), 449-455.  http://pubs.acs.org/cgi-bin/abstract.cgi/joceah/2006/71/i02/abs/jo0513008.html

Parker, Kathlyn A.; Chang, Wonsuk. Regioselectivity of Rhodium Nitrene Insertion. Syntheses of Protected Glycals of L-Daunosamine, D-Saccharosamine, and L-Ristosamine. Organic Letters  (2005),  7(9),  1785-1788.  http://pubs.acs.org/cgi-bin/abstract.cgi/orlef7/2005/7/i09/abs/ol050356l.html

Parker, Kathlyn A.; Su, Dai-Shi. Models for the synthesis of pluramycin antibiotics. Rearrangement of mono-protected aminoglycal-substituted cyclohexadienediols. Journal of Carbohydrate Chemistry  (2005),  24(2), 199-208.  http://search.epnet.com/login.aspx?direct=true&dp=aph&an=17678372

Parker, Kathlyn A.; Su, Dai-Shi. The "reverse polarity" approach to ravidomycin. Aryl C-aminoglycosides from a lithiated aminoglycal. Journal of Carbohydrate Chemistry (2005),  24(2),  187-197.  http://search.epnet.com/login.aspx?direct=true&dp=aph&an=17678372

#Parker, Kathlyn A.; Lim, Yeon-Hee. The Total Synthesis of (-)-SNF4435 C and (+)-SNF4435 D.    Journal of the American Chemical Society (2004), 126(49), 15968-15969.  http://pubs.acs.org/cgi-bin/abstract.cgi/jacsat/2004/126/i49/abs/ja044733l.html

Parker, Kathlyn A.; Katsoulis,  A. A Strategy for Exploiting the Pseudosymmetry of the C1-C13 Stretch of Discodermolide.  Organic Letters  (2004), 6(9), 1413-1416.  http://pubs.acs.org/cgi-bin/abstract.cgi/orlef7/2004/6/i09/abs/ol049735p.html

Parker, Kathlyn A.; Lim, Yeon-Hee. "Endo" and "Exo" Bicyclo[4.2.0]-octadiene Isomers from the Electrocyclization of Fully Substituted Tetraene Models for SNF 4435C and D. Control of Stereochemistry by Choice of a Functionalized Substituent. Organic Letters  (2004),  6(2),  161-164.  http://pubs.acs.org/cgi-bin/abstract.cgi/orlef7/2004/6/i02/abs/ol036048+.html

Parker, Kathlyn A.; Chang, Wonsuk.A Synthesis of L-Vancosamine Derivatives from Non-Carbohydrate Precursors by a Short Sequence Based on the Marshall, McDonald, and Du Bois Reactions.  Organic Letters  (2003),  5(21),  3891-3893.  http://pubs.acs.org/cgi-bin/abstract.cgi/orlef7/2003/5/i21/abs/ol035479p.html

Parker, Kathlyn A.; Mindt, Thomas L. Heterocycle Annulation of Enolizable Vinyl Quinone Imides. Dihydroquinolines and Quinolines from Thermal 6p -Electrocyclizations and Indoles from Photochemical Cyclizations. Organic Letters  (2002),  4(24),  4265-4268.  http://pubs.acs.org/cgi-bin/abstract.cgi/orlef7/2002/4/i24/abs/ol026849x.html

Parker, Kathlyn A.; Mindt, Thomas L. Electrocyclic ring closure of the enols of vinyl quinones. A 2H-chromene synthesis.  Organic Letters  (2001), 3(24), 3875-3878.  http://pubs.acs.org/cgi-bin/abstract.cgi/orlef7/2001/3/i24/abs/ol0167199.html

Oliver, John S.; Parker, Kathlyn A.; Suggs, J. William. Effect of the Universal Base 3-Nitropyrrole on the Selectivity of Neighboring Natural Bases.  Organic Letters  (2001),  3(13),  1977-1980. http://pubs.acs.org/cgi-bin/abstract.cgi/orlef7/2001/3/i13/abs/ol015966+.html

Parker, Kathlyn A.; Ding, Qing-Jie.   A general approach to angucyclines: synthesis of hatomarubigin A, rubiginone B2, antibiotic X-1488E, 6-hydroxytetrangulol, and tetrangulol.    Tetrahedron  (2000), 56(52), 10249-10254. http://dx.doi.org Enter 10.1016/S0040-4020(00)00869-3

Parker, Kathlyn A.; Ding, Qing-Jie. Relative reactivities of amino glycosides and their synthetic equivalents in the C-glycosylation of aromatics. Synthesis of the pseudo-aglycon (D-C-glycoside) of the benzanthrins. Tetrahedron  (2000),  56(52),  10255-10261. http://dx.doi.org Enter 10.1016/S0040-4020(00)00868-1

Parker, Kathlyn A.; Georges, Asimina T. Reductive Aromatization of Quinols: Synthesis of the C-Arylglycoside Nucleus of the Papulacandins and Chaetiacandin. Organic Letters  (2000),  2(4),  497-499.  http://pubs.acs.org/cgi-bin/abstract.cgi/orlef7/2000/2/i04/abs/ol991346l.html

Parker, Kathlyn A.; Dermatakis, Apostolos. Tetrahydroimidazo[1,5,4-ef][1,5]benzodiazepinones: Synthesis and Evaluation as HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors.Journal of Organic Chemistry (1997),  62(12), 4164-4167.  http://pubs.acs.org/cgi-bin/article.cgi/joceah/1997/62/i12/html/jo962050l.html

Parker, Kathlyn A.; Dermatakis, Apostolos. Enantioselective Synthesis of the Enyne A-Ring Synthon of the 1a -Hydroxy Vitamins D. Journal of Organic Chemistry (1997), 62(19), 6692-6696. http://pubs.acs.org/cgi-bin/article.cgi/joceah/1997/62/i19/html/jo970957t.html

Parker, Kathlyn A.; Ledeboer, Mark W. Asymmetric Reduction. A Convenient Method for the Reduction of Alkynyl Ketones. Journal of Organic Chemistry (1996), 61(9), 3214-17.  http://pubs.acs.org/cgi-bin/article.cgi/joceah/1996/61/i09/html/jo951712o.html

Parker, Kathlyn A.; Su, Dai-Shi.Synthesis of C-Aryl Furanosides by the "Reverse Polarity" Strategy. Journal of Organic Chemistry  (1996),  61(6), 2191-4. http://pubs.acs.org/cgi-bin/article.cgi/joceah/1996/61/i06/html/jo951344o.html

Parker, Kathlyn A.; Resnick, Lynn. The First Total Synthesis of a Pyripyropene-type ACAT Inhibitor, (± )-GERI-BP001. Journal of Organic Chemistry  (1995),  60(17),  5726-8. http://pubs3.acs.org/acs/journals/doilookup?in_doi=10.1021/jo00122a074

Parker, Kathlyn A.; Coburn, Craig A.; Koh, Yung-hyo  Reductive and Nonreductive Aromatization of Quinol Ketal Glycals. Models for the Preparation of C-Aryl Glycoside Natural Products.    Journal of Organic Chemistry (1995), 60(9), 2938-41.  http://pubs3.acs.org/acs/journals/doilookup?in_doi=10.1021/jo00114a057

Parker, Kathlyn A.; Koh, Yung-hyo. Methodology for the Regiospecific Synthesis of Bis C-Aryl Glycosides. Models for Kidamycins. Journal of the American Chemical Society (1994),  116(24),  11149-50. http://pubs.acs.org/cgi-bin/archive.cgi/jacsat/1994/116/i24/pdf/ja00103a037.pdf

Parker, Kathlyn A..Novel methods for the synthesis of C-aryl glycoside natural products. Pure and Applied Chemistry (1994), 66(10/11), 2135-8.  http://www.iupac.org/publications/pac/1994/pdf/6610x2135.pdf

Parker, Kathlyn A.; Fokas, Demosthenes. The Radical Cyclization Approach to Morphine. Models for Highly Oxygenated Ring-III Synthons. Journal of Organic Chemistry (1994), 59(14),  3933-8.  http://pubs.acs.org/cgi-bin/archive.cgi/joceah/1994/59/i14/pdf/jo00093a027.pdf

Parker, Kathlyn A.; Fokas, Demosthenes. Stereochemistry of Radical Cyclizations to Side-Chain Olefinic Bonds. An Approach to Control of the C-9 Center of Morphine. Journal of Organic Chemistry (1994), 59(14), 3927-32.  http://pubs.acs.org/cgi-bin/archive.cgi/joceah/1994/59/i14/pdf/jo00093a026.pdf

Parker, Kathlyn A.; Fokas, Demosthenes. Convergent synthesis of (± )-dihydroisocodeine in 11 steps by the tandem radical cyclization strategy.  A formal total synthesis of (± )-morphine.    Journal of the American Chemical Society (1992), 114(24), 9688-9.  http://pubs.acs.org/cgi-bin/archive.cgi/jacsat/1992/114/i24/pdf/ja00050a075.pdf

Parker, Kathlyn A.; Coburn, Craig A.; Johnson, Paul D.; Aristoff, Paul. Reductive aromatization of quinols. New convenient methods for the regiospecific synthesis of p-hydroxy C-aryl glycals.    Journal of Organic Chemistry (1992),  57(20),  5547-50.  http://pubs.acs.org/cgi-bin/archive.cgi/joceah/1992/57/i20/pdf/jo00046a049.pdf

Parker, Kathlyn A.; Kim, Ho Jin.  A short stereospecific synthesis of (dl)-lycoramine. Control of relative stereochemistry by dipole effects.  Journal of Organic Chemistry  (1992),  57(2),  752-5.  http://pubs.acs.org/cgi-bin/archive.cgi/joceah/1992/57/i02/pdf/jo00028a066.pdf

Parker, Kathlyn A.; Coburn, Craig A.Regioselectivity in intramolecular nucleophilic aromatic substitution. Synthesis of the potent anti HIV-I 8-halo TIBO analogs. Journal of Organic Chemistry  (1992),  57(1),  97-100.  http://pubs.acs.org/cgi-bin/archive.cgi/joceah/1992/57/i01/pdf/jo00027a019.pdf

Parker, Kathlyn A.; Coburn, Craig A. Reductive aromatization of quinol ketals:  a new synthesis of C-aryl glycosides. Journal of the American Chemical Society  (1991),  113(22),  8516-18. http://pubs.acs.org/cgi-bin/archive.cgi/jacsat/1991/113/i22/pdf/ja00022a046.pdf

Parker, Kathlyn A.; Coburn, Craig A. A four-step synthesis of TIBO R82150. Journal of Organic Chemistry  (1991), 56(15), 4600-1.  http://pubs.acs.org/cgi-bin/archive.cgi/joceah/1991/56/i15/pdf/jo00015a007.pdf

Parker, Kathlyn A.; Coburn, Craig A. A strategy for the convergent synthesis of gilvocarcins via chromium carbene benzannulation.  1-O-Methyldefucogilvocarcin V in seven steps. Journal of Organic Chemistry  (1991),  56(4),  1666-8.  http://pubs.acs.org/cgi-bin/archive.cgi/joceah/1991/56/i04/pdf/jo00004a058.pdf

 [Erratum to document cited in CA114(9):82308r]. Journal of Organic Chemistry (1992), 57(4),  1318. 

Parker, Kathlyn A.; Ruder, Suzanne M. Vinylquinone ketals as Diels-Alder dienes.  Construction of functionalized naphthalenes and nonlinear polycyclic aromatics. Journal of the American Chemical Society  (1989),  111(15),  5948-9.  http://pubs.acs.org/cgi-bin/archive.cgi/jacsat/1989/111/i15/pdf/ja00197a069.pdf

Parker, Kathlyn A.; Spero, Denice M.; Van Epp, James. Radical cyclizations in conformationally restrained systems.  Generation of the cis,cis-hexahydrophenanthro[4,5-bcd]furan tetracycle of morphine. Journal of Organic Chemistry  (1988),  53(19), 4628-30.  http://pubs.acs.org/cgi-bin/archive.cgi/joceah/1988/53/i19/pdf/jo00254a053.pdf

Parker, Kathlyn A.; Casteel, Dee Ann  Isoquinoline quinones.  Preparation of saframycin intermediates and a total synthesis of mimosamycin. Journal of Organic Chemistry  (1988),  53(12),  2847-50.  http://pubs.acs.org/cgi-bin/archive.cgi/joceah/1988/53/i12/pdf/jo00247a038.pdf

Parker, Kathlyn A.; Meschwitz, Susan M. Short stereoselective synthesis of L-nogalose.    Carbohydrate Research  (1988),  172(2),  319-26.  http://dx.doi.org Enter 10.1016/S0008-6215(00)90867-X 

Parker, Kathlyn A.; Iqbal, Tahir.  New approaches to the synthesis of vitamin D metabolites. 2.  Effect of some substituents on stereochemistry in the intramolecular cycloadditions of nonatrienes. Journal of Organic Chemistry  (1987),  52(19),  4369-77.  http://pubs.acs.org/cgi-bin/archive.cgi/joceah/1987/52/i19/pdf/jo00228a040.pdf

Parker, Kathlyn A. Cyclization approaches to the synthesis of natural products.  Nat. Prod. Chem., Proc. Int. Symp. Pak.-U.S. Binatl. Workshop, 1st  (1986),  Meeting Date 1984, 307-17. 

Parker, Kathlyn A.; Iqbal, Tahir.N,N-Dimethylaniline as a solvent for intramolecular Diels-Alder reactions.  Improved yields and changes in stereoisomer ratios.  Tetrahedron Letters  (1986),  27(52), 6291-4.  http://dx.doi.org Enter  10.1016/S0040-4039(00)87789-8 

Parker, Kathlyn A.; Koziski, Kathleen A. Directed hydroxylation of aromatics. Journal of Organic Chemistry (1987), 52(4),  674-6. http://pubs.acs.org/cgi-bin/archive.cgi/joceah/1987/52/i04/pdf/jo00380a034.pdf

Parker, Kathlyn A.; Spero, Denice M.; Koziski, Kathleen A. Evaluation of some preparations of trialkoxyphthalic acid derivatives.  Journal of Organic Chemistry  (1987),  52(2), 183-8. http://pubs.acs.org/cgi-bin/archive.cgi/joceah/1986/51/i21/pdf/jo00371a020.pdf

Lawler, Ronald G.; Parker, Kathlyn A.  Efficient distillation in the microscale laboratory. Journal of Chemical Education  (1986),  63(11),  1012. 

Parker, Kathlyn A.; Farmar, James G. A stereocontrolled synthesis of dl-biflora-4,10(19),15-triene.Journal of Organic Chemistry  (1986),  51(21),  4023-8. http://pubs.acs.org/cgi-bin/archive.cgi/joceah/1986/51/i21/pdf/jo00371a020.pdf

Parker, Kathlyn A.; Breault, Gloria A. Strategies and intermediates for fredericamycin A synthesis. A 3-substituted 9-alkoxycyclopenta[g]isoquinoline-1,8(2H)-dione.  Tetrahedron Letters  (1986),  27(33),  3835-8.  http://dx.doi.org Enter  10.1016/S0040-4039(00)83892-7 

Parker, Kathlyn A.; Spero, Denice M.; Inman, Karen C.  Aryl radical-initiated cyclizations:  effect of aryl substituents on ring-size.  Tetrahedron Letters  (1986),  27(25),  2833-6.  http://dx.doi.org Enter  10.1016/S0040-4039(00)84654-7  

Parker, Kathlyn A.; Farmar, James G.  Regioselectivity in the Claisen rearrangement of bis-allylic alcohols:  electronic and steric effects of C-4 substituents.  Tetrahedron Letters  (1985),  26(31),  3655-8.  http://dx.doi.org Enter  10.1016/S0040-4039(00)89215-1 

Parker, Kathlyn A.; Koziski, Kathleen A.; Breault, Gloria. Synthesis of 2,2-disubstituted 4,9-dihydroxy-1H-benz[f]indene-1,3(2H)-diones. A model sequence for the synthesis of fredericamycin.  Tetrahedron Letters  (1985), 26(18),  2181-2.  http://dx.doi.org Enter  10.1016/S0040-4039(00)98956-1

Parker, Kathlyn A.; Tallman, Elizabeth A.  Annelative phenol synthesis.  Preparation of 7-methyljuglone and 7,9,11-trideoxydaunomycinone.   Tetrahedron  (1984),  40(22),  4781-8.  http://dx.doi.org Enter  10.1016/S0040-4020(01)91540-6 

Parker, Kathlyn A.; Cohen, Isaac D.; Padwa, Albert; Dent, William. Cycloadditions of non-stabilized azomethine ylides and quinones.  Synthesis of the Reniera isoindole.  Tetrahedron Letters  (1984),  25(43),  4917-20. http://dx.doi.org Enter  10.1016/S0040-4039(01)91258-4 

Parker, Kathlyn A.; Cohen, Isaac D.; Babine, Robert E. Approaches to the isoquinoline quinone antibiotics.  Additions of an amino acid derivative to a quinone monoacetal.  Tetrahedron Letters  (1984),  25(33), 3543-6. C http://dx.doi.org Enter  10.1016/S0040-4039(01)91071-8 

Parker, Kathlyn A.; O'Fee, Robert.  Halonium-initiated cyclizations of allylic urethanes:  stereo- and regioselectivity in functionalizing the olefinic bond.  Journal of the American Chemical Society  (1983), 105(3), 654-5. http://pubs.acs.org/cgi-bin/archive.cgi/jacsat/1983/105/i03/pdf/ja00341a073.pdf

Parker, Kathlyn A.; Babine, Robert E.  Revision of assignment of structure to the pyrrolodiazepinone antitumor antibiotic sibiromycin.  Journal of the American Chemical Society  (1982), 104(25), 7330-1.  http://pubs.acs.org/cgi-bin/archive.cgi/jacsat/1982/104/i25/pdf/ja00389a079.pdf

Parker, Kathlyn A.; O'Fee, Robert P.  Amidopalladation of tertiary allylic amines and of terminal olefins with phthalimide and N-methyltoluenesulfonamide.  Journal of Organic Chemistry  (1983),  48(9), 1547-50.  http://pubs.acs.org/cgi-bin/archive.cgi/joceah/1983/48/i09/pdf/jo00157a037.pdf

Parker, Kathlyn A.; Babine, Robert E.  Revision of the assignment of relative stereochemistry in sibirosamine: synthesis of methyl N-toluenesulfonyl-a -D-sibirosaminopyranoside.  Tetrahedron Letters  (1982), 23(17), 1763-6. http://dx.doi.org Enter 10.1016/S0040-4039(00)86735-0 

Parker, Kathlyn A.; Petraitis, Joseph J.; Kosley, Raymond W., Jr.; Buchwald, Stephen L.  Reactions of propargyl alcohols with amide acetals.  Journal of Organic Chemistry  (1982), 47(3), 389-98.  http://pubs.acs.org/cgi-bin/archive.cgi/joceah/1982/47/i03/pdf/jo00342a002.pdf

Parker, Kathlyn A.; Iqbal, Tahir. New approaches to the synthesis of vitamin D metabolites.  1.  Stereocontrol in the intramolecular Diels-Alder reaction.  Journal of Organic Chemistry  (1982),  47(2), 337-42.  http://pubs.acs.org/cgi-bin/archive.cgi/joceah/1982/47/i02/pdf/jo00341a031.pdf

Parker, Kathlyn A.; Sworin, Michael E. Assignment of regiochemistry to substituted naphthoquinones by chemical and spectroscopic method; amino-, hydroxy-, and bromojuglone derivatives.  Journal of Organic Chemistry  (1981),  46(16),  3218-23.  http://pubs.acs.org/cgi-bin/archive.cgi/joceah/1981/46/i16/pdf/jo00329a014.pdf

Parker, Kathlyn A.; Petraitis, Joseph J. Synthesis of ansamycins: an approach to the naphthoquinone portion of the rifamycins and streptovaricins.  Tetrahedron Letters  (1981),  22(5),  397-400.  http://dx.doi.org Enter 10.1016/0040-4039(81)80109-8 

Parker, Kathlyn A.; Kallmerten, James. Efficient, regiospecific synthesis of anthracycline intermediates:  total synthesis of daunomycin.  Journal of the American Chemical Society  (1980),  102(18),  5881-6.  http://pubs.acs.org/cgi-bin/archive.cgi/jacsat/1980/102/i18/pdf/ja00538a029.pdf

Parker, Kathlyn A.; Kallmerten, James. Approaches to anthracyclines.  2.  Regiospecific annulative quinone synthesis. Journal of Organic Chemistry  (1980),  45(13),  2620-5.  http://pubs.acs.org/cgi-bin/archive.cgi/joceah/1980/45/i13/pdf/jo01301a016.pdf

Parker, Kathlyn A.; Kallmerten, James. Approaches to anthracyclines.  1.  Conjugate aroylation of a ,b -unsaturated esters.  Journal of Organic Chemistry  (1980),  45(13),  2614-20.  http://pubs.acs.org/cgi-bin/archive.cgi/joceah/1980/45/i13/pdf/jo01301a015.pdf

Parker, Kathlyn A.; Iqbal, Tahir. Approaches to anthracyclines:  efficient syntheses of substituted naphthylacetonitriles. Journal of Organic Chemistry  (1980), 45(6), 1149-51. http://pubs.acs.org/cgi-bin/archive.cgi/joceah/1980/45/i06/pdf/jo01294a045.pdf

Parker, Kathlyn A.; Kang, Suck-Ku. Regiospecific nucleophilic aromatic substitution:  conjugate addition of active methylene compounds to quinone monoacetals and aromatization of the adducts.  Journal of Organic Chemistry  (1980),  45(7),  1218-24. http://pubs.acs.org/cgi-bin/archive.cgi/joceah/1980/45/i07/pdf/jo01295a010.pdf

Parker, Kathlyn A.; Andrade, John R. Studies on the synthesis of a -functionalized quinols:  synthesis of jacaranone.  Journal of Organic Chemistry  (1979),  44(22),  3964-6.  http://pubs.acs.org/cgi-bin/archive.cgi/joceah/1979/44/i22/pdf/jo01336a046.pdf

Parker, Kathlyn A.; Fedynyshyn, Theodore H.  Synthesis of anhydrosibiromycinone: a new method for the direct synthesis of pyrrolo-1,4-benzodiazepin-5-ones.   Tetrahedron Letters  (1979),  (19),  1657-60.  http://dx.doi.org Enter  10.1016/S0040-4039(01)93616-0 

Parker, Kathlyn A.; Kallmerten, James L.  Regiospecific synthesis of linear quinone systems: efficient convergent synthesis of anthracycline intermediates.   Tetrahedron Letters  (1979),   (14),  1197-200.  http://dx.doi.org Enter  10.1016/S0040-4039(01)86101-3 

Parker, Kathlyn A.; Kang, Suck-Ku.  Convergent approaches to indoloquinones:  additions to quinone monoimides.  Journal of Organic Chemistry  (1979),  44(9),  1536-40. http://pubs.acs.org/cgi-bin/archive.cgi/joceah/1979/44/i09/pdf/jo01323a034.pdf

Parker, Kathlyn A.; Sworin, Michael.  A convergent synthesis of indoloquinones.  Tetrahedron Letters (1978), (26),  2251-4.  http://dx.doi.org Enter  10.1016/S0040-4039(01)91504-7 

Parker, Kathlyn A.; Adamchuk, Mark R.  Intramolecular Diels-Alder reactions of the furan diene. Tetrahedron Letters  (1978),   (19),  1689-92.  http://dx.doi.org Enter  10.1016/S0040-4039(01)94641-6

Parker, Kathlyn A.; Kallmerten, James L.  Conjugate nucleophilic aroylation of a ,b -unsaturated esters.   Tetrahedron Letters  (1977),  (52), 4557-60.  http://dx.doi.org Enter  10.1016/S0040-4039(01)83567-X 

Parker, Kathlyn A.; Petraitis, Joseph J.   A general synthesis of tertiary allenic amides: the reaction of propargyl alcohols with diethylformamide acetals.  Tetrahedron Letters  (1977),   (52),  4561-4.  http://dx.doi.org Enter  10.1016/S0040-4039(01)83568-1 

Parker, Kathlyn A.; Kosley, Raymond W., Jr.; Buchwald, Stephen L.; Petraitis, Joseph J.  The reaction of tertiary ethynyl alcohols with formamide acetals:  formation of dienamines and enamine orthoformates.   Journal of the American Chemical Society  (1976),  98(22),  7104-5.  http://pubs.acs.org/cgi-bin/archive.cgi/jacsat/1976/98/i22/pdf/ja00438a074.pdf

Parker, Kathlyn A.; Kosley, Raymond W., Jr. The amide acetal condensation of propargyl alcohols.  Synthesis of g -keto esters and silyl allenes under mild conditions.   Tetrahedron Letters  (1976),   (5),  341-4.  http://dx.doi.org Enter  10.1016/S0040-4039(00)93726-2  

Parker, Kathlyn A.; Kosley, Raymond W., Jr  New dienamine synthesis.  Amide acetal Claisen rearrangement of alkynyl allylic alcohols.  Tetrahedron Letters (1975), (35), 3039-40.  http://dx.doi.org Enter  10.1016/S0040-4039(00)75066-0

Parker, Kathlyn A.; Gibbons, E. Grant.  Direct synthesis of primary amides from grignard reagents.  Tetrahedron Letters  (1975),  (12),  981-4. http://dx.doi.org Enter  10.1016/S0040-4039(00)72622-0 

Parker, Kathlyn A.; Kosley, Raymond W., Jr.   Stereoselective synthesis of functionalized olefins.  Orthoester Claisen rearrangement of alkynyl allylic alcohols.  Tetrahedron Letters  (1975),  (9),  691-4.  http://dx.doi.org Enter  10.1016/S0040-4039(00)71957-5

Book chapter.  Parker, Kathlyn A. Aryl C-glycosides by the reverse polarity approach. ACS Symposium Series  (2005),  896(Glycomimetics),  93-105. 

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